New selective PAD4 inhibitors binding a calcium-deficient form of the PAD4 enzyme have validated the critical enzymatic role of human and mouse PAD4 in both histone citrullination and neutrophil extracellular lure formation for, to our awareness, The very first time. The therapeutic prospective of PAD4 inhibitors can now be explored. https://waldox110juf3.wikitelevisions.com/user