There's a launch of norepinephrine within the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors from the dorsal horn to decrease afferent pain transmission and produce analgesia. As a result, medication like clonidine that focus on alpha-2 receptors can affect the transmission of suffering. Clonidine is a protracted-term medication. https://pr6bookmark.com/story19929826/5-easy-facts-about-onolidine-described